Burning desire

Usually the burning desires we have are a confirmation of what God has called us to do. Would you be burning inside from the thought your desire WOULD NOT COME TO PASS? Just the thought of it not happening - is there pain there?  If you came to the end of your life and you didn't go to Bible College or build that building or start that work program for the homeless would it hurt you inside? Would you be in anguish because you did not fulfill that desire? It's not too late.